Hepatoprotective effects of Malva sylvestris L. against paracetamol-induced hepatotoxicity
نویسندگان
چکیده
Liaqat HUSSAIN, Javaria IKRAM, Kanwal REHMAN, Muhammad TARIQ, Muhammad IBRAHIM, Muhammad Sajid Hamid AKASH* College of Pharmacy, Government College University Faisalabad, Faisalabad, Pakistan Institute of Pharmacology, Toxicology, and Biochemical Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, P.R. China Department of Applied Chemistry, Faculty of Science and Technology, Government College University Faisalabad, Faisalabad, Pakistan
منابع مشابه
Antioxidant and Hepatoprotective Effects of Bauhinia racemosa Against Paracetamol and Carbon Tetrachloride Induced Liver Damage in Rats
The methanol extract of Bauhinia racemosa Lam. (Caesalpiniaceae) stem bark was investigated for the antioxidant and hepatoprotective effects in Wistar albino rats. Different groups of animals were administered with paracetamol (500 mg/kg, (p.o.) once in a day for 7 days) and carbon tetrachloride (CCl4) (30 % CCl4, 1 ml/kg b.wt. in liquid paraffin 3 doses (i.p.) at 72 h interval). The methanol e...
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Background: Malva sylvestris L. (M. sylvestris) has antioxidant property and is widely used in the traditional medicine to treat gastrointestinal, respiratory, skin and urological disorders. Objective: In this study, the protective effect of M. sylvestris against sodium fluoride-induced nephrotoxicity in the rat was evaluated. Methods: The M. sylvestris flower extract was prepared and in...
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Paracetamol (PCM) is widely used as analgesic and antipyretic drug, but at high dose it leads to undesirable side effects, such as hepatotoxicity. This study gives the information about hepatoprotective activity of abelmoschus moschatus seed extract against paracetamol and ethanol induced hepatotoxicity. Paracetamol induce hepatotoxicity was evaluated by an increase (P<0.05) in serum AST, ALT, ...
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Background & Aim: The human body has the liver as one of its largest organs. It serves as the major site for metabolism and excretion. Injury to the liver or impairment of its functions may complicate one’s health and therefore, constitutes one of the serious public health challenges. The ethanol seed extract of Citrus paradisi Macfad (CPE) was carried out to evaluate ...
متن کاملHepatoprotective Properties of Ethanol Seed Extract of Citrus paradisi Macfad (Grape Fruit) Against Paracetamol-Induced Hepatotoxicity in Wistar Rats
Background & Aim: The human body has the liver as one of its largest organs. It serves as the major site for metabolism and excretion. Injury to the liver or impairment of its functions may complicate one’s health and therefore, constitutes one of the serious public health challenges. The ethanol seed extract of Citrus paradisi Macfad (CPE) was carried out to evaluate ...
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